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F-Actin (Smooth Muscle) Ab, IgG by ELISA 19 Units or less Negative 20-30 Units Weak Positive - Suggest repeat testing in two to three weeks with fresh specimen. 31 Units or greater …
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A negative SMA or actin antibody test and an increased titer of LKM1 may indicate autoimmune hepatitis type 2. Type 2 is uncommon in the United States. If the SMA or actin antibody test and other antibody tests are negative, then symptoms and liver injury may be due to causes other than autoimmune hepatitis.
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Antibody to F-actin was found in only one serum and no controls. Thus in different liver diseases the reactivity of antibodies to monomeric G-actin and polymeric F-actin may differ, presumably because of specificity for different determinants of the actin molecule. Reactivity to G-actin may distinguish a group of alcoholic subjects in whom a ...
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The antigen specificity of anti-SMAs in the context of AIH has been identified as filamentous-actin (F-actin).(2) Because the clinical symptoms of AIH are nonspecific, being found in a variety of liver diseases (drug/alcohol-associated hepatitis, viral hepatitis, primary sclerosing cholangitis, etc), the diagnosis can be challenging.
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Actin (Smooth Muscle) Antibody (IgG) – Actin is the major antigen to which smooth muscle antibodies react in autoimmune hepatitis. F-Actin IGG antibodies are found in 52-85% of patients with Autoimmune Hepatitis (AIH) or chronic active hepatitis and in 22% of patients with Primary Biliary Cirrhosis (PBC). Anti-Actin antibodies have been reported in 3-18% of sera from normal …
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Actin is a key structural protein of the cytoskeleton network that is particularly abundant in intestinal microvilli. IgA class anti-actin antibodies, detectable by either an immunofluorescence or ELISA technique, seem to contribute to villus cytoskeleton damage and to the pathogenesis of intestinal damage in celiac disease.
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Anti-Actin, beta antibodies are available from several suppliers. In humans, this protein is encoded by the gene ACTB. The protein may also be known as BRWS1, PS1TP5BP1, actin, cytoplasmic 1, and I(2)-actin. The reported amino acid length is 375 and the expected mass is 41.7 kDa.
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Specificity. This antibody recognises beta and gamma actin in Human samples. It probably also recognises all the other known forms of Human actin. This antibody detects a single clean band in Human, Mouse, Rat, Chicken and Drosophila samples. In Xenopus laevis a …
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An enlarged liver, abdominal pain, unexplained weight loss, dark urine, and pale stools, and a yellowish pallor of the skin are other symptoms that may prompt the medical practitioner to call for a smooth muscle antibody blood test. At the outset an actin smooth muscle antibody test may be performed as the presence of anti-actin antibodies is ...
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Anti-Actin Antibody (C-2) is a mouse monoclonal IgG 1 κ Actin antibody, cited in 2,187 publications, provided at 200 µg/ml; specific for an epitope mapping between amino acids 357-375 at the C-terminus of Actin of human origin; Actin Antibody (C-2) is recommended for detection of a broad range of Actin isoforms of mouse, rat, human, and Xenopus origin by WB, IP, IF, IHC(P), FCM and …
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A number of studies have reported on antibodies to cytoskeletal actin in the context of celiac disease [119][120][121]. Although these antibodies are not specific to celiac disease and have also ...
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A new diagnostic tool (algorithm-1) for coeliac disease (CD) permitting the diagnosis without performing the duodenal biopsy has been recently proposed by the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN). It combines symptoms associated with CD, high anti-transglutaminase type 2 antibody (anti-TG2) levels, anti-endomysium-IgA antibodies …
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In addition, the removal of circulating antibodies by thoracic duct drainage or plasma exchange results in improvement in MG symptoms. Anti-AChR antibodies in human MG are comprised of the IgG subclass 1 or 3 and mainly target the main immunogenic region of the AChR, which is located at the extracellular region of the AChR-α subunit [13,14].
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For this reason, antibodies raised to β-actin may cross-react with γ-actin, and vice versa. α-cardiac and α-skeletal actin are expressed in striated cardiac and skeletal muscles, respectively; two smooth muscle actins, α- and γ-actin, are found primarily in vascular smooth …
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Actin (Smooth Muscle) Antibody (IgG) - Actin is the major antigen to which smooth muscle antibodies react in autoimmune hepatitis. F-Actin IGG antibodies are found in 52-85% of patients with Autoimmune Hepatitis (AIH) or chronic active hepatitis and in 22% of patients with Primary Biliary Cirrhosis (PBC). Anti-Actin antibodies have been reported in 3-18% of sera from normal healthy controls.
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Actin antibody Information, Symptoms, Treatments and Resources. Overview. Posts. Posts on Actin antibody (25035) Can it be AIH with no elevated liver enzymes or SED rate? - Hepatitis Autoimmune Community - Sep 18, 2009.
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A negative SMA or actin antibody test and an increased titer of LKM1 may indicate autoimmune hepatitis type 2. Type 2 is uncommon in the United States. If the SMA or actin antibody test and other antibody tests are negative, then symptoms and liver injury may be due to causes other than autoimmune hepatitis. Is there anything else I should know?
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Detection of alpha ‑Smooth Muscle Actin in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human a-Smooth Muscle Actin …
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The anti-smooth muscle antibody (ASMA) test is used to diagnose autoimmune hepatitis and distinguish it from other causes of liver damage. Learn about the test and what its results mean.
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F-Actin (Smooth Muscle) Antibody, IgG by ELISA with Reflex to Smooth Muscle Antibody, IgG Titer. Feedback . Feedback. I want to provide feedback regarding Comment. First Name. Last Name. Email. …
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A negative SMA or actin antibody test and an increased titer of LKM1 may indicate autoimmune hepatitis type 2. Type 2 is uncommon in the United States. If the SMA or actin antibody test and other antibody tests are negative, then symptoms and liver injury may be due to causes other than autoimmune hepatitis.
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A negative SMA or actin antibody test and an increased titer of LKM1 may indicate autoimmune hepatitis type 2. Type 2 is uncommon in the United States. If the SMA or actin antibody …
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beta ‑Actin in NIH‑3T3 Mouse Cell Line. beta -Actin was detected in immersion fixed NIH-3T3 mouse embryonic fibroblast cell line using Mouse Anti-Human/Mouse/Rat beta -Actin Monoclonal Antibody (Catalog # MAB8929) at 0.1 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and ...
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Beta Actin antibody Rabbit Polyclonal from Proteintech validated in Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC) applications. This antibody reacts with human, mouse, rat, monkey, canine samples. .No. 20536-1-AP. KD/KO Validated.
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The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to …
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Description: Actin Smooth Muscle Antibody Blood Test. This test measures the level of Actin Smooth Muscle Antibodies (ASMA) in the blood. Smooth muscle antibodies are produced in people with …
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Anti-β-Actin Antibody (C4) is a mouse monoclonal IgG 1 κ β-Actin antibody, cited in 11,068 publications, provided at 200 µg/ml; raised against gizzard Actin of chicken origin; Anti-beta-Actin Antibody (C4) is recommended for detection of β-Actin of mouse, rat, human, avian, bovine, canine, porcine, rabbit, Dictyostelium discoideum and Physarum polycephalum origin by WB, IP, IF, IHC(P) …
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These antibodies have been verified by Relative expression, Cell treatment and Knockdown to confirm specificity to beta Actin. Find the beta Actin antibody that fits your needs. Choose from 1 of 54 beta Actin antibodies, which have been validated in experiments with 1429 publications and 414 images featured in our data gallery.
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Reliably and specifically detect actin using this Anti-Actin Antibody, clone C4. This highly published monoclonal antibody is validated for use in ELISA, IC, IF, IH, IH(P) & WB. This mAb is also available …
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These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to Actin. Find the Actin antibody that fits your needs. Choose from 1 of 22 Actin antibodies, which have been validated in experiments with 657 publications and 159 images featured in our data gallery.
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